Karuppiah Muthumani Selected Research

3-phenyl-4,5-dihydro-5-isoxazole acetic acid

3/2016	Safety, bioavailability, and pharmacokinetics of VGX-1027-A novel oral anti-inflammatory drug in healthy human subjects.
8/2014	VGX-1027 modulates genes involved in lipopolysaccharide-induced Toll-like receptor 4 activation and in a murine model of systemic lupus erythematosus.

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Karuppiah Muthumani Research Topics

Disease

14	Infections 01/2017 - 10/2002
3	Rheumatoid Arthritis 03/2016 - 08/2011
3	Communicable Diseases (Infectious Diseases) 01/2016 - 01/2003
3	Neoplasms (Cancer) 01/2009 - 10/2004
2	Virus Diseases (Viral Diseases) 01/2016 - 12/2008
2	Hypoxia (Hypoxemia) 01/2015 - 03/2014
2	HIV Infections (HIV Infection) 03/2009 - 03/2004
2	Melanoma (Melanoma, Malignant) 01/2009 - 11/2006
2	Inflammation (Inflammations) 12/2002 - 01/2002
1	Pneumonia (Pneumonitis) 01/2017
1	Human Influenza (Influenza) 01/2017
1	Emerging Communicable Diseases (Emerging Infectious Diseases) 01/2016
1	Zika Virus Infection 01/2016
1	Weight Loss (Weight Reduction) 01/2016
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 08/2014
1	Pleurisy (Pleuritis) 08/2014
1	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 08/2014
1	Autoimmune Diseases (Autoimmune Disease) 08/2014
1	Systemic Lupus Erythematosus (Libman-Sacks Disease) 08/2014
1	Chronic Limb-Threatening Ischemia 03/2014
1	Necrosis 03/2014
1	Ischemia 03/2014
1	Congenital Abnormalities (Deformity) 11/2012
1	Joint Diseases (Joint Disease) 08/2011
1	Arthritis (Polyarthritis) 08/2011
1	Bacterial Infections (Bacterial Infection) 07/2010

Drug/Important Bio-Agent (IBA)

6	Proteins (Proteins, Gene)FDA Link 01/2015 - 03/2004
5	VaccinesIBA 01/2017 - 01/2003
4	DNA (Deoxyribonucleic Acid)IBA 01/2017 - 11/2006
4	DNA VaccinesIBA 01/2016 - 01/2003
3	vpr Gene ProductsIBA 03/2009 - 11/2006
2	3-phenyl-4,5-dihydro-5-isoxazole acetic acidIBA 03/2016 - 08/2014
2	A-Form DNA (A-DNA)IBA 01/2016 - 11/2006
2	Antiviral Agents (Antivirals)IBA 08/2015 - 03/2004
2	Amino Acids FDA Link 10/2013 - 01/2009
2	Peptides (Polypeptides)IBA 10/2013 - 01/2009
2	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 09/2011 - 03/2004
2	AntigensIBA 12/2008 - 01/2002
2	Caspase 9IBA 12/2002 - 10/2002
1	Formaldehyde (Formol)FDA Link 01/2017
1	NucleoproteinsIBA 01/2017
1	Respiratory Syncytial Virus VaccinesIBA 01/2017
1	InterferonsIBA 01/2016
1	Toll-Like Receptor 4IBA 08/2014
1	OligonucleotidesIBA 08/2014
1	Acetic Acid (Vinegar)FDA LinkGeneric 08/2014
1	LipopolysaccharidesIBA 08/2014
1	Hematoxylin (Haematoxylon)IBA 03/2014
1	Eosine Yellowish-(YS) (Eosin)IBA 03/2014
1	Transcription Factors (Transcription Factor)IBA 03/2014
1	AntibodiesIBA 03/2014
1	HLA-DQB1 antigen (HLA DQB1)IBA 10/2013
1	EnzymesIBA 09/2011
1	Nucleocapsid ProteinsIBA 09/2011
1	ChemokinesIBA 08/2011
1	Interleukin-6 (Interleukin 6)IBA 08/2011
1	CytokinesIBA 08/2011
1	Interleukin-8 (Interleukin 8)IBA 08/2011
1	Interleukin-10 (Interleukin 10)IBA 08/2011
1	Indicators and Reagents (Reagents)IBA 01/2009
1	Viral ProteinsIBA 04/2004
1	p38 Mitogen-Activated Protein KinasesIBA 03/2004
1	MitogensIBA 03/2004
1	Phosphotransferases (Kinase)IBA 03/2004
1	Annexin A5IBA 03/2004
1	phosphatidylglucosaminylglycerolIBA 01/2003
1	Caspase 8 (Caspase-8)IBA 10/2002

Therapy/Procedure

5	Therapeutics 01/2016 - 10/2004
1	Lasers (Laser) 03/2014
1	Organ Transplantation 11/2012